Final answer:
Long-term use of crack cocaine can have adverse effects on the cardiovascular and respiratory systems, as well as psychological effects.
Step-by-step explanation:
Long-term use of crack cocaine can have several adverse effects on the body.
1. **Cardiovascular effects**: Crack cocaine use can lead to an increased risk of stroke, heart attack, cardiac arrhythmia, and sudden cardiac death. The drug constricts blood vessels, increasing blood pressure and straining the heart.
2. **Respiratory effects**: Smoking crack cocaine can cause lung injury and respiratory symptoms. It can worsen preexisting lung diseases and increase the risk of hospital admissions and premature mortality.
3. **Psychological effects**: Chronic use of crack cocaine can lead to symptoms such as depression, decreased ability to feel pleasure, and subjective fatigue.