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WHAT COMMON TESTS ARE PEROFRMED ON POCT?

User Jjst
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Final answer:

Common tests performed on POCT include absorption screening, metabolic stability screening, in vitro cytochrome P450 inhibitory screening, plasma protein binding, and in vivo pharmacokinetic screening.

Step-by-step explanation:

Common tests that are performed on point-of-care testing (POCT) include:

  • Absorption screening (n-octanol/water, PAMPA, Caco-2 cells)
  • Metabolic stability screening (microsomes, hepatocytes)
  • In vitro cytochrome P450 inhibitory screening (microsomes, human recombinant enzymes)
  • Plasma protein binding (ultrafiltration, equilibrium dialysis)
  • In vivo pharmacokinetic screening (cassette dosing, pooling samples)
User Noufal Kmc
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