Final answer:
The desired periapical tissue responses after endodontic therapy on a tooth with a periapical lesion include regeneration of dentin, regeneration of alveolar bone, and re-establishment of the periodontal ligament.
Step-by-step explanation:
The desired periapical tissue responses after endodontic therapy on a tooth with a periapical lesion include (a) regeneration of dentin; (b) regeneration of alveolar bone; and (d) re-establishment of the periodontal ligament. Therefore, the correct answer is (a), (b), and (d).