Final answer:
Alpha-blockers and beta-blockers are the two classes of drugs used for diagnosis and management of Pheochromocytoma and to treat hypertension. Phenoxybenzamine, an alpha-blocker, is used preoperatively to manage hypertension, while beta-blockers like propranolol control tachycardia. Beta-blockers should be used after alpha-blockade has been established to avoid adverse effects.
Step-by-step explanation:
The question refers to the management and diagnostic use of drugs in the treatment of Pheochromocytoma, which is a type of tumor of the adrenal gland that secretes excess catecholamines leading to hypertension. The medications typically used for both diagnosis and management of Pheochromocytoma, as well as for treating hypertension, are α-blockers and β-blockers. For example, Phenoxybenzamine, an irreversible nonselective α-blocker, is used to manage hypertension in patients with Pheochromocytoma before surgical intervention. Furthermore, β-blockers such as propranolol are utilized to control the tachycardia and arrhythmias caused by excess catecholamines. It is important to note that β-blockers should only be administered after adequate α-blockade to prevent unopposed α-adrenergic receptor stimulation, which can lead to a dangerous increase in blood pressure.