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_____ is a common site for metastases in many cancers survivors with metazoic disease to the bone require modifications to their exercise program

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Final answer:

The bone is a common site for metastases, which is the spread of cancer cells from a primary tumor to a distant site through the bloodstream. Such conditions require modifications to exercise programs for cancer survivors with bone metastases.

Step-by-step explanation:

The bone is a common site for metastases in many cancers. When cancer cells spread from a primary tumor to a distant site, a process known as metastasis, they can travel through the bloodstream and grow in new areas. The most common places for these secondary cancers to occur are the brain, lungs, bones, and liver. In the case of exercise programs for cancer survivors with metastatic disease to the bone, modifications are necessary to accommodate the individual's health status and to ensure safety.