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Rhogam : given at ___ weeks, ___ hours post partum, IM. Only given to Rh _____ mother. Also if indirect Coomb's test is ____, don't need to give Rhogam cuz she has antibody only give if _____ coombs

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Final answer:

RhoGAM is an IM injection given to prevent HDN at 26-28 weeks of pregnancy and within 72 hours postpartum to Rh-negative mothers, unless the indirect Coombs' test is positive, indicating preexisting antibodies.

Step-by-step explanation:

RhoGAM is administered to an Rh-negative mother at 26-28 weeks of pregnancy and within 72 hours postpartum, typically via an intramuscular (IM) injection. It is specifically given to prevent the development of Rh antibodies that could lead to hemolytic disease of the newborn (HDN) in future Rh-positive pregnancies. If the indirect Coombs' test is positive, indicating that the mother already has Rh antibodies, RhoGAM is not needed because it's only effective in preventing the formation of antibodies, not in combating already existing ones. The drug is only given if the indirect Coombs' test is negative, showing that the mother has not yet developed these antibodies. The medication is not necessary if the indirect Coombs test is negative, but if the coombs test is positive, RhoGAM is needed to prevent an immune response.

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