Final answer:
The medication needs of newborns' (neonates') and premature infants' are different from those of older infants and children due to the immaturity of their kidneys, some endocrine systems, nervous systems, and blood-brain barriers.
Step-by-step explanation:
The medication needs of newborns' (neonates') and premature infants' are different from those of older infants and children because their kidneys, some endocrine systems, nervous systems, and blood-brain barriers are not mature. These immaturities have various effects on the metabolism, excretion, immune system, and nervous system of newborns, making it necessary to adjust medication dosages and types for newborns. For example, the immature kidneys of neonates can result in impaired metabolism and excretion of medications, necessitating careful consideration of drug doses and administration.