Final answer:
Drugs such as opioids, benzodiazepines, and barbiturates often lead to tolerance and withdrawal, necessitating more of the drug for the same effect and causing adverse symptoms when stopped.
Step-by-step explanation:
The group of drugs that tend to produce tolerance and withdrawal includes opioids like heroin and prescription painkillers, as well as benzodiazepines and barbiturates. These substances can lead to both physical and psychological dependence, requiring more of the drug to experience the same effects and causing negative symptoms when use is discontinued.
Drug withdrawal can manifest in various uncomfortable or even life-threatening symptoms, which are often opposite to the effects of the drug. For example, withdrawal from sedatives may result in arousal and agitation, while opioid withdrawal can resemble severe flu symptoms. Medications like methadone or buprenorphine can help manage these symptoms in the rehabilitation process.