Final answer:
Some anti-cytokine agents used in rheumatoid arthritis include TNF inhibitors like infliximab, adalimumab, and etanercept; interleukin inhibitors such as tocilizumab and anakinra; and hydroxychloroquine as well as corticosteroids for their anti-inflammatory effects.
Step-by-step explanation:
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease characterized by the activation of CD4 T cells and the release of pro-inflammatory cytokines like IL-1, IL-6, and TNF-α. Anti-cytokine agents are among the diverse treatment options available for RA, which aim to reduce the damage to bone and cartilage by inhibiting the inflammatory response. Common anti-cytokine medications include biological agents such as tumor necrosis factor inhibitors (TNFi), e.g., infliximab, adalimumab, and etanercept; and interleukin inhibitors such as tocilizumab (IL-6 inhibitor) and anakinra (IL-1 inhibitor). Hydroxychloroquine is another example, often used in combination with other therapies to address inflammation. Additionally, corticosteroids are employed for their powerful anti-inflammatory effects. These treatments aim to alleviate symptoms and slow the progression of the disease.