Final answer:
False positive mono spot tests occur when the test results show a positive indication for infectious mononucleosis (mono) even though the person does not have the infection.
Step-by-step explanation:
False positive mono spot tests occur when the test results show a positive indication for infectious mononucleosis (mono) even though the person does not have the infection.
The false-positive results can happen due to previous infections with other viruses that have similar antigens and can cross-react with the mono spot test. For example, people with hepatitis or rubella may have elevated levels of heterophile antibodies that can lead to a false positive result.
To confirm a positive mono spot test, a second, more specific test called the heterophile antibody test is performed.