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When do false positive mono spot tests occur

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Final answer:

False positive mono spot tests occur when the test results show a positive indication for infectious mononucleosis (mono) even though the person does not have the infection.

Step-by-step explanation:

False positive mono spot tests occur when the test results show a positive indication for infectious mononucleosis (mono) even though the person does not have the infection.

The false-positive results can happen due to previous infections with other viruses that have similar antigens and can cross-react with the mono spot test. For example, people with hepatitis or rubella may have elevated levels of heterophile antibodies that can lead to a false positive result.

To confirm a positive mono spot test, a second, more specific test called the heterophile antibody test is performed.

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