Question

Down syndrome is a genetic disorder that is also called trisomy 21 a person with down syndrome has an extra copy of chromosome

21 which detail best describes the genetic mutation that results in down syndrome

Answer 1

Down syndrome, also known as Trisomy 21, is a genetic disorder caused by an extra copy of chromosome 21. The genetic mutation that results in Down syndrome is called chromosomal nondisjunction during meiosis. People with Down syndrome may experience mental and physical impairments, but with proper support, they can lead fulfilling lives.

Step-by-step explanation:

Down syndrome, also known as Trisomy 21, is a genetic disorder caused by an extra copy of chromosome 21. Normally, humans have 46 chromosomes, but individuals with Down syndrome have 47 chromosomes, with three copies of chromosome 21.

The genetic mutation that results in Down syndrome is called chromosomal nondisjunction during meiosis. This is when the chromosomes fail to separate properly, leading to an extra copy of chromosome 21 in the egg or sperm. The frequency of nondisjunction events increases with age, particularly in females over 36.

People with Down syndrome may experience mental and physical impairments, and they often have distinct facial features. However, with proper assistance and support, individuals with Down syndrome can lead fulfilling lives.