The amount of intracellular glucose in hepatocytes and skeletal muscle cells d) Inhibits fatty acid oxidation . Therefore , d) Inhibits fatty acid oxidation is correct .
AMP (adenosine monophosphate) plays a crucial role in cellular energy regulation through its interaction with AMP-activated protein kinase (AMPK).
AMPK is a key enzyme that acts as a cellular energy sensor, helping to maintain energy balance by regulating various metabolic pathways.
However, inhibiting fatty acid oxidation is not a direct method by which AMP regulates the amount of intracellular glucose in hepatocytes and skeletal muscle cells.
Let's briefly discuss the other options to provide a comprehensive understanding:
a) Stimulates gluconeogenesis: AMPK can indeed stimulate gluconeogenesis, the process by which glucose is synthesized from non-carbohydrate precursors.
This is a way to generate glucose when cellular energy levels are low.
b) Inhibits glycogenolysis: AMPK activation can inhibit glycogenolysis, the breakdown of glycogen into glucose units.
This helps to conserve glucose and maintain energy balance.
c) Stimulates glucose uptake: AMPK activation promotes glucose uptake in skeletal muscle cells.
This is important for replenishing cellular energy stores during periods of increased energy demand.
d) Inhibits fatty acid oxidation: While AMPK activation can inhibit fatty acid synthesis, it does not directly inhibit fatty acid oxidation.
In fact, AMPK tends to stimulate fatty acid oxidation to generate ATP and meet energy demands.
Option d is not a method by which AMP regulates the amount of intracellular glucose, as AMPK's role in lipid metabolism primarily involves promoting fatty acid oxidation rather than inhibiting it.
Question
which is not a method by which amp regulates the amount of intracellular glucose in hepatocytes and skeletal muscle cells?
a) Stimulates gluconeogenesis
b) Inhibits glycogenolysis
c) Stimulates glucose uptake
d) Inhibits fatty acid oxidation