Question

Analyze this pedigree, and answer ALL of the following questions: a. What type of disorder is represented in this pedigree? b. Imagine that you are Individual #11. Do you have the disorder? c. If you produce offspring with a female whose phenotype is the same as Individual #14, what is the likelihood that your children will have the disorder? d. What is the likelihood that they will carry the disorder?

Answer 1

The disorder represented in this pedigree is recessive, and individuals with the disorder have the genotype aa. Individual #11 does not have the disorder.

Step-by-step explanation:

In this pedigree, the disorder is represented by individuals indicated in blue, and they have the genotype aa. Unaffected individuals are indicated in yellow and can have the genotype AA or Aa.

Individual #11 is unaffected, as indicated by their yellow color in the pedigree. Therefore, they do not have the disorder.

If Individual #11 produces offspring with a female whose phenotype is the same as Individual #14 (blue color), the likelihood that their children will have the disorder depends on the genotype of the female. If the female is homozygous for the disorder (aa), there is a 100% likelihood that their children will have the disorder. If the female is heterozygous (Aa), there is a 50% likelihood.

The likelihood that the children will carry the disorder depends on the genotype of Individual #11. If Individual #11 is heterozygous (Aa), there is a 50% likelihood that the children will carry the disorder.