Question

An individual has the following sequences on his chromosomes in the region of an STR:

--------TGGCTGGCTGGCTGGC------------

--------TGGCTGGCTGGCTGGCTGGCTGGCTGGCTGGC------------

If you amplify these STRs and subject the products to capillary electrophoresis, how many peaks will you see on the electropherogram?
a. One
b. Two
c. Four and eight
d. One and two

Answer 1

The capillary electrophoresis of the individual's STR sequences will result in an electropherogram with two peaks, because there are two distinct alleles for the STR region. Therefore correct option is B

Step-by-step explanation:

The individual in question has two different STR (Short Tandem Repeat) sequences on their chromosomes. When these STRs are amplified and subjected to capillary electrophoresis, the resulting electropherogram will show two peaks. This is because there are two distinct alleles for the STR region, one with three repeats of the sequence (TGGC) and another with seven repeats. Capillary electrophoresis separates these amplified STR sequences based on their size, resulting in two peaks corresponding to the two different alleles present.