Final answer:
Introns in the initial pre-mRNA are removed during processing, and the remaining exons are spliced together to form a mature mRNA that codes for a protein. This explains why a 5000-nucleotide pre-mRNA can produce a protein of roughly 500 amino acids. The answer is option E.
Step-by-step explanation:
A pre-mRNA molecule that is 5000 nucleotides long makes a protein consisting of approximately 500 amino acids, which is likely due to the presence of introns in the pre-mRNA. These introns are non-coding sequences that are removed during pre-mRNA processing.
The remaining exons, which are regions that code for amino acids, are spliced together to form the mature mRNA. Each set of three nucleotides, known as a codon, corresponds to one amino acid, so the length of the protein correlates with the number of triplets in the exonic sequence of the mRNA, not the length of the unprocessed pre-mRNA.