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Large quantities of what, can cause hypertension and edema?

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Final answer:

Consuming large amounts of sodium chloride (salt) can cause hypertension and edema by increasing blood pressure and disrupting fluid balance, particularly in individuals with underlying health issues or protein deficiencies.

Step-by-step explanation:

Large quantities of sodium chloride (NaCl), commonly known as salt, can cause hypertension (high blood pressure) and edema (swelling caused by excess fluid trapped in the body's tissues). Excess consumption of NaCl, especially above the daily requirement of 5-20 grams, increases blood pressure in hypertensive patients, which can lead to further health complications such as heart failure and damage to blood vessels. In the presence of a protein deficiency, the body's ability to maintain proper fluid balance is compromised, resulting in edema. Conditions such as heart failure, liver cirrhosis, kidney disease, and certain medications can also contribute to hypervolemia, which is excessive fluid volume due to the retention of water and sodium.

Effective management of these conditions includes reversing the factors that triggered the hypervolemia, which can help restore the body's homeostasis. In the case of chronic and severe liver disease, a decrease in the production of plasma proteins leads to a reduction in colloid osmotic pressure, further contributing to edema. Therefore, treating the underlying medical issue is crucial for alleviating edema and maintaining fluid balance.

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