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One of the few hormones that functions on a positive-feedback loop is:

User Bee Smears
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Oxytocin is a hormone associated with labor and childbirth and is regulated by a positive feedback loop. It amplifies uterine contractions until the baby is born, contrasting with the homeostatic effects of negative feedback mechanisms in the endocrine system.

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The Role of Oxytocin in Positive Feedback Loops

One of the few hormones that functions on a positive-feedback loop is oxytocin. This hormone, which is particularly significant during labor and childbirth, is an example where positive feedback results in an amplified response. During childbirth, as uterine contractions intensify, they stimulate the release of more oxytocin from the pituitary gland, which in turn causes more intense contractions. This cycle continues until the birth of the infant. Positive feedback loops amplify the hormonal response until the end goal is achieved, contrasting with negative feedback loops that act to maintain a stable state within the body.

While most endocrine hormones are regulated by negative feedback mechanisms, oxytocin during labor is a textbook example of a hormone regulated by a positive feedback loop. Understanding these feedback mechanisms is essential for identifying how various hormonal levels are controlled and the potential consequences when these systems are disrupted, such as in the case of diabetes mellitus.

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