Final answer:
The kidneys are not a body location usually impacted by edema; they function in osmoregulation, not swelling. Causes of edema include underlying medical conditions and certain drugs, and treatment focuses on the underlying cause.
Step-by-step explanation:
The body location that is not usually impacted by edema is the kidneys. Edema is the accumulation of excess water in the tissues and is most commonly seen in the soft tissues of the extremities and dependent areas of the body. The lungs can also be affected by pulmonary edema. However, the kidneys themselves do not swell with edema; instead, they play a role in the regulation of fluid balance. Causes of edema include underlying medical conditions such as congestive heart failure, kidney disease, vein disorders in the legs, and liver disorders, but may also be due to the usage of non-steroidal anti-inflammatory drugs, estrogen therapies, and some diabetes medications. Therapy for edema focuses on treating the underlying cause and may include elevation of affected limbs, appropriate exercises, massage, compression, and dietary changes such as reduced salt intake.