98.1k views
0 votes
Where are calcium ions stored before a signaling pathway releases them into the cytosol?

1 Answer

3 votes

Final answer:

Calcium ions are stored in the endoplasmic reticulum and released into the cytosol during signaling events, activating various cellular processes depending on the cell type.

Step-by-step explanation:

Calcium ions (Ca²+) are fundamental second messengers in various signaling pathways in cells. These ions are stored in cytoplasmic vesicles, predominantly within the endoplasmic reticulum (ER) and also in the sarcoplasmic reticulum in muscle cells. When a signaling process is triggered, ligand-gated or other types of ion channels open, allowing the stored Ca²+ to be released into the cytosol, increasing its concentration. This release can activate numerous enzymes and processes, depending on the cell type—such as insulin secretion in pancreatic ß-cells or muscle contractions in muscle cells. In addition, Ca²+ pumps work to restore low cytosolic Ca²+ levels after the signaling event has passed.

User Jitendra Solanki
by
8.7k points