Final answer:
U.S. adolescents show a decrease in tobacco use, variable trends in other drug uses, including a notable rise in prescription medication misuse. There's also a noted decrease in alcohol and marijuana usage.
Step-by-step explanation:
The current trend in U.S. adolescents' drug use shows decreases in tobacco use and some fluctuations in the use of other drugs, including a significant increase in the use of prescription medications for non-medical purposes. This aligns with the ongoing opioid crisis, where an increase in prescription painkiller use led to more heroin use when prescription opioids became harder to obtain. Moreover, rates of use of alcohol and marijuana have seen significant decreases, coinciding with changing public perceptions and legal status of these substances.