105k views
0 votes
What is the potential risk associated with consuming foods high in tyramine while taking certain medications used to treat depression, like MAOIs?

a) Gastrointestinal discomfort
b) Hypertensive crisis
c) Allergic reactions
d) Drowsiness

User Pheona
by
7.5k points

1 Answer

2 votes

Final answer:

Consuming foods high in tyramine while on MAO inhibitors can lead to a hypertensive crisis due to the accumulation of neurotransmitters. It is crucial for patients on MAOIs to manage their diet to avoid this dangerous increase in blood pressure. Drowsiness is typically a side effect of tricyclic antidepressants, not related to tyramine-MAOI interactions.

Step-by-step explanation:

The potential risk associated with consuming foods high in tyramine while taking MAO inhibitors is a hypertensive crisis, which is a sudden and severe increase in blood pressure. MAOIs block the action of monoamine oxidase, an enzyme responsible for breaking down neurotransmitters like norepinephrine, dopamine, and serotonin. When a person consumes foods high in tyramine while on MAOIs, this can lead to an excessive accumulation of these neurotransmitters, causing a dangerous rise in blood pressure that could become life-threatening. It is vital for individuals on MAOIs to follow specific dietary guidelines to reduce their tyramine intake.

Drowsiness could be a side effect of medications like tricyclic antidepressants but is not typically associated with the tyramine-MAOI interaction. The effect of tricyclic antidepressants, such as imipramine, can cause sleepiness and a decrease in blood pressure among normal subjects. In contrast, prolonged use of these medications yields mood elevation in depressed patients.

User Arifa Chan
by
7.4k points