Question

Substance abuse sharply reduces the number of _____ receptors in the brain's reward system.

a) Dopamine
b) Serotonin
c) GABA
d) Glutamate

Answer 1

Substance abuse commonly results in a sharp reduction in the number of dopamine receptors in the brain's reward system.

Step-by-step explanation:

The brain's reward system is significantly affected by substance abuse, which often leads to a reduction in the number of dopamine receptors. Dopamine is a critical neurotransmitter for the reward pathway, and its function is associated with the experience of pleasure and reward. Drugs such as cocaine, amphetamine, and other psychostimulants increase dopamine neurotransmission, which can eventually lead to a decrease in the sensitivity and density of dopamine receptors in the brain due to overstimulation. Therefore, the correct answer to the question is a) Dopamine receptors.