Final answer:
Statement 1 is true, relatives of those with major depressive disorder are at an increased risk for depression. Relatives of those with mania are at an increased risk for bipolar disorder.
Step-by-step explanation:
The correct answer is d. Only Statement 1 is true. Relatives of those with major depressive disorder are at an increased risk for depression, not mania. On the other hand, relatives of those with mania are at an increased risk for bipolar disorder (which includes episodes of mania and depression).