Final answer:
The correct option is D. The invention of the printing press is the event that occurred during the Renaissance but not before Shakespeare was born, around 1450, playing a key role in the dissemination of ideas that characterized the period.
Step-by-step explanation:
The event that would have taken place during the Renaissance but NOT before Shakespeare was born is D. Invention of the printing press. The printing press was invented by Johannes Gutenberg in the mid-15th century and played a significant role in spreading knowledge and ideas during the Renaissance.
It allowed for the mass production of books and pamphlets, which in turn fueled the development of Humanism and the spread of new knowledge.