Final answer:
It is true that as components elute from the column in chromatography, they pass into a detector where a physicochemical property is measured, producing a chromatogram.
Step-by-step explanation:
The statement that as the components elute from the column they pass into a detector where some physicochemical property of the analyte is measured is true. In chromatographic separations, the sample's components partition between a mobile phase and a stationary phase based on their differing interactions with each phase. As the components separate, they elute at different times and are detected. The detector's response is plotted as a function of elution time or volume of mobile phase, generating a chromatogram.
Using chromatography, analysts can perform not only separation of analytes and interferents but also qualitative or quantitative analysis of the analyte. The retention time signifies the time each solute takes to pass through the column, with sharper peaks indicating better separation. Chromatography can separate complex mixtures, including those of inks or drugs and their metabolites, which are essential for accurate bioanalytical assays and pharmacokinetic studies.