Final answer:
Woodrow Wilson was the Democratic President who established the Federal Trade Commission to regulate big businesses, supported by the Clayton Antitrust Act of 1914.
Step-by-step explanation:
The Democratic President who created the Federal Trade Commission (FTC) to regulate big business was Woodrow Wilson. The FTC was established to enforce federal regulations, promoting fair competition and protecting consumers and small businesses from unfair or anticompetitive practices.
President Wilson supported the Clayton Antitrust Act of 1914, which helped clarify and strengthen antitrust laws. This act addressed issues such as conflicts of interest on corporate boards, required government approval for mergers and acquisitions, banned various unfair business practices, and protected labor unions from being treated as illegal monopolies.