Final answer:
The Na+ channels are closed during rest, open during depolarization, and closed during repolarization of an excitable cell.
Step-by-step explanation:
The correct answer is A. Closed during rest, open during depolarization, and closed during repolarization.
During rest, the sodium (Na+) channels in an excitable cell are closed. When the cell depolarizes, meaning the membrane potential becomes more positive, the Na+ channels open to allow sodium ions to enter the cell. This influx of positive charge leads to the depolarization of the cell. During repolarization, the Na+ channels close again, restoring the resting state of the cell.