Question

Type of eukaryotic post-transcriptional modification, enhances stability, important for ribosome binding, prevents degradation by exonuclease at this end.

A) 5'-Capping
B) Polyadenylation
C) Splicing
D) Methylation

Answer 1

5'-Capping is the post-transcriptional modification that enhances mRNA stability, facilitates ribosome binding, and prevents exonuclease degradation at the 5' end by adding a protective 7-methylguanosine cap.

Step-by-step explanation:

The type of eukaryotic post-transcriptional modification that enhances stability, is important for ribosome binding, and prevents degradation by exonucleases at one end is 5'-Capping.

During the transcription process, while the pre-mRNA is still being synthesized, a 7-methylguanosine cap is added to the 5' end of the growing transcript via a phosphate linkage. This cap acts as a protective shield against exonuclease degradation and is recognized by factors involved in protein synthesis, which then help to initiate translation by ribosomes.