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Which of the following statements is CORRECT regarding enzyme-substrate encounter probability?

a) Higher temperature increases encounter probability
b) Larger substrate size decreases encounter probability
c) Higher enzyme concentration decreases encounter probability
d) Higher pH increases encounter probability

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Final answer:

The correct statement about enzyme-substrate encounter probability is that a higher temperature typically increases the likelihood of encounters between enzyme and substrate, as long as the temperature is within the enzyme's optimal range.

Step-by-step explanation:

The correct statement regarding enzyme-substrate encounter probability is that higher temperature increases encounter probability. To elaborate:

  • Higher temperature increases the kinetic energy of molecules, resulting in more frequent collisions between enzymes and substrates, thus increasing the probability of encounters until an optimal temperature is reached.
  • Larger substrate size can potentially decrease encounter probability because it may make it more difficult for the substrate to fit into the enzyme's active site.
  • Higher enzyme concentration generally increases the likelihood that a substrate will encounter an enzyme, thus increasing the reaction rate, provided there is sufficient substrate present.
  • The effect of pH on enzyme activity is highly dependent on the specific enzyme and its optimal pH range. Therefore, a higher pH does not universally increase encounter probability; it depends on whether the higher pH aligns with the enzyme’s optimal working conditions.

Thus, the correct option regarding enzyme-substrate encounter probability is 'a) Higher temperature increases encounter probability' assuming the temperature is within the enzyme's optimal working range.

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