Final answer:
In the 1950s, Rosalind Franklin used X-ray diffraction methods to demonstrate the helical nature of DNA, while Watson and Crick formulated the double-stranded structural model of DNA.
Step-by-step explanation:
In the 1950s, scientists Rosalind Franklin, James Watson, and Francis Crick made significant contributions to understanding the structure of DNA. Franklin used X-ray diffraction methods to demonstrate the helical nature of DNA, providing crucial data. Watson and Crick used Franklin's data, along with other researchers' findings, to formulate the double-stranded structural model of DNA. Their work led to the discovery of the Z-DNA structure.