Final answer:
The initiator tRNA is formylated in prokaryotes but not in eukaryotes, making the statement partially true. Eukaryotic initiator tRNA carries methionine that is not formylated, therefore the correct answer to the question is False.
Step-by-step explanation:
For eukaryotes and prokaryotes, the statement that the initiator tRNA is a formylated Methionine tRNA (fMet:tRNA) is only partially true. In prokaryotes, such as E. coli, the initiator tRNA indeed carries a formylated methionine (fMet-tRNAMet) to start protein synthesis. However, in eukaryotes, the initiator tRNA (called Met-tRNAi), which also binds to the start codon AUG, carries a methionine that is not formylated. Hence, methionine is never formylated in eukaryotic initiator tRNA. Additionally, eukaryotes do not have a formylase enzyme to remove the formyl group because it is absent from their initiation process. Thus, the correct answer to the question is B) False.