Final answer:
The incorrect statement about transcription factors is that there are 6 highly conserved Eukaryotic General Transcription Factors; there are more than 6, each designated with 'TFII' plus a letter. TFIID, with its TBP subunit, binds the TATA box and bends DNA to form a transcription initiation complex, while bromodomains bind to acetylated lysine residues aiding transcription activation.
Step-by-step explanation:
The statement which is incorrect about transcription factors is that there are 6 highly conserved Eukaryotic General Transcription Factors. There are actually several general transcription factors, not only 6, and they are designed with the acronym TFII followed by another letter (A-J), indicating different types. For example, TFIID is one of the first factors to bind to the TATA box in the promoter during the transcription initiation phase. It includes a TATA-binding protein (TBP) subunit which plays a crucial role in the bending of DNA, thus aiding in the formation of the transcription initiation complex. The bromodomain, on another note, recognizes and binds to acetylated lysine residues, facilitating the recruitment of additional transcription machinery and chromatin remodeling factors necessary for transcription activation.