Final answer:
The methylation pattern on DNA influences the binding of transcription factors, affecting gene expression by either repressing or facilitating the binding of these proteins to the DNA. It does not directly affect ribosomes, RNA polymerase, or spliceosomes.
Step-by-step explanation:
The methylation pattern on DNA affects the binding of transcription factors. Methylation typically acts to repress gene expression by inhibiting the binding of transcription factors to the DNA, thereby preventing transcription. In some contexts, methylation can also promote gene expression by facilitating the binding of certain proteins to the methylated DNA. However, methylation does not directly influence the binding of ribosomes, RNA polymerase, or spliceosomes to the DNA. Instead, ribosomes bind to the mRNA molecule during translation, RNA polymerase binds to the promoter DNA sequence to initiate transcription, and spliceosomes are involved in the splicing of introns during the processing of pre-mRNA.