Final answer:
Charged or polar (hydrophilic) side chains are found on the exterior of proteins, while hydrophobic (nonpolar) side chains are buried inside to maintain a stable protein structure.
Step-by-step explanation:
In the context of protein structure, charged or polar side chains typically are found on the exterior of a protein because they can interact favorably with the aqueous environment, which means they are hydrophilic.
On the other hand, hydrophobic (nonpolar) side chains tend to be sequestered in the interior of proteins to avoid water and create a stable protein structure. Therefore, the correct statement is: Hydrophilic (charged) side chains are found on the outside while hydrophobic (nonpolar) side chains are found clustered together on the inside.
This categorization helps to maintain the protein's stability in its native environment and contributes to its overall functionality.