Question

Both miRNA and siRNA work in conjunction with

a) RNA polymerase to bind RNA transcripts in the nucleus.
b) a protein complex called RISC to bind RNA transcripts in the cytoplasm.
c) hairpin structures to bind RNA transcripts in the cytoplasm.
d) a protein complex called RISC to bind RNA transcripts in the nucleus.

Answer 1

Both miRNA and siRNA associate with a protein complex called RISC to bind RNA transcripts in the cytoplasm, a process that is part of the regulatory mechanism known as RNA interference. Option a is answer

Step-by-step explanation:

Both miRNA and siRNA work in conjunction with b) a protein complex called RISC to bind RNA transcripts in the cytoplasm.

These small RNA molecules are involved in a process known as RNA interference, which is a biological mechanism in eukaryotic cells that regulates gene expression and protects against viral infections. MiRNA and siRNA are produced as longer precursors that are then processed by the enzyme Dicer into mature forms.

These mature RNA molecules associate with RISC, guiding it to bind to complementary mRNA sequences. SiRNA-RISC complexes lead to the cleavage and degradation of targeted mRNA, while miRNA-RISC complexes can either degrade mRNA or inhibit its translation, depending on the degree of complementarity between the miRNA and its target. Option a is answer