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Gaucher's disease breaks down ___ by taking the head group and forms ceramide.

A. Sphingolipids
B. Glycerophospholipids
C. Cholesterol
D. Glycolipids

1 Answer

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Final answer:

Gaucher's disease affects the metabolism of glycolipids, with glucocerebrosides accumulating due to deficient glucocerebrosidase, leading to the formation of ceramide.

Step-by-step explanation:

Gaucher's disease specifically affects the metabolism of sphingolipids. In this disease, the enzyme glucocerebrosidase, which normally breaks down glucocerebrosides by removing the glucose molecule, is deficient or dysfunctional.

Without the proper function of this enzyme, glucocerebrosides accumulate in various organs, leading to the symptoms of the disease. Since glucocerebrosides are a type of glycolipid and the question refers to breakdown resulting in ceramide, the correct answer is D. Glycolipids. Glycolipids are sphingolipids that contain a carbohydrate attached to the sphingosine part of ceramide.

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