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What are the key steps in single-stranded model of homologous DNA recombination?

A) Strand invasion, heteroduplex formation, and Holliday junction resolution.
B) Bidirectional unwinding, base excision, and RNA primer synthesis.
C) Mismatch repair, exonuclease activity, and ligase-mediated sealing.
D) Transcription initiation, translation elongation, and replication termination.

User Mquandalle
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Final answer:

The single-stranded model of homologous DNA recombination involves strand invasion, heteroduplex formation, and Holliday junction resolution to repair DNA breaks.

Step-by-step explanation:

The key steps in the single-stranded model of homologous DNA recombination are strand invasion, heteroduplex formation, and Holliday junction resolution. During strand invasion, a DNA strand with a single-strand break invades a homologous DNA double helix. This leads to heteroduplex formation, where the invading strand pairs with its complementary strand, forming hybrid DNA. Finally, Holliday junction resolution occurs where these recombination intermediates are cleaved and ligated to generate two intact DNA helices, repairing the DNA structure.

The key steps in the single-stranded model of homologous DNA recombination are strand invasion, heteroduplex formation, and Holliday junction resolution. In this process, a single-stranded DNA molecule invades a homologous double-stranded DNA molecule. This results in the formation of a heteroduplex, which is a region where the single-stranded DNA is paired with the complementary strand of the double-stranded DNA. Finally, the Holliday junction, which is a structure formed during recombination, is resolved through enzymatic cleavage and branch migration.

User Reloader
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