Final answer:
The statement is false because each gene has specific replication timing dependent on its activity and is not replicated simultaneously during the S phase.
Step-by-step explanation:
The statement is False because replication timing is specific to each gene and cell type. Gene expression and replication are indeed related processes. While DNA replication is a universal process that occurs during the S phase of the cell cycle, not all genes are replicated simultaneously. The timing of replication can be influenced by a gene's activity; for example, genes that are actively expressed are typically replicated earlier in S phase. Additionally, certain areas of the genome called replicons, which contain multiple origins of replication, ensure that the entire DNA is replicated efficiently during the S phase. This orchestrated timing ensures that the overall structure and function of the chromatin are maintained.