Final answer:
The major causes of mutation in DNA are exposure to UV radiation, DNA replication errors, and chemical mutagens.
Step-by-step explanation:
The three major causes of mutation in DNA are:
- Exposure to UV radiation: UV radiation from the sun or artificial sources can cause mutations by damaging the DNA structure. This can lead to alterations in the nucleotide sequence.
- DNA replication errors: Mistakes can occur during the process of DNA replication, resulting in changes to the sequence of nucleotides.
- Chemical mutagens: Chemical substances, such as certain industrial chemicals or tobacco smoke, can act as mutagens and cause DNA damage and mutations.