Final answer:
The key combination that opens the Task Manager is Ctrl + Shift + Esc.
Step-by-step explanation:
The correct key combination to open the Task Manager is Ctrl + Shift + Esc.
Pressing these keys simultaneously will open the Task Manager directly without any additional steps. This is a quick and convenient way to access the Task Manager, which allows you to monitor and manage the processes and applications running on your computer.
It is important to note that the other key combinations mentioned in the options have different functions: Ctrl + Alt + Del brings up a menu including the option to open Task Manager, Alt + F4 closes the currently active window, and Win + R opens the Run dialog box.