Final answer:
Replication in the study was achieved by having a large group of similarly characterized subjects, by measuring consistent variables across participants, and by having roughly equal numbers of participants in each treatment group, enhancing the reliability of the findings.
Step-by-step explanation:
In the experiment examining the effects of blood-building drugs on brain development in prematurely born babies, replication was demonstrated by having multiple subjects that had similar characteristics, specifically all the babies were premature and weighed less than three pounds (Option A).
Additionally, the replication aspect appears in the consistent measurement of variables across all participants of the study, as the babies were evaluated on intelligence, language, and memory (Option B).
Lastly, the replication can also be seen in the number of infants per treatment group as there were 53 infants in the study, divided roughly equally across the three different treatments which included administering erythropoietin (EPO), darbepoetin, or giving no treatment (Option D and E). Replication is crucial in scientific research to ensure that results are reliable and not due to chance or outlier effects.