Question

Which of the following statements is true?

A) Opiates are Na channel blockers and local anesthetic is a Ca2+ channel blocker
B) NSAIDs are COX inhibitors and naloxone is an opiate agonist
C) Opiates are Ca2+ channel blockers and local anesthetic is Na channel blockers
D) NSAIDs are COX inhibitors and local anesthetic is a Ca2+ channel blocker

Answer 1

The correct statement is: D) NSAIDs are COX inhibitors and local anesthetic is a Ca2+ channel blocker. Local anesthetics work by blocking voltage-gated sodium channels to provide pain relief, while NSAIDs inhibit the enzyme COX to reduce inflammation and pain.

Step-by-step explanation:

The correct statement is: D) NSAIDs are COX inhibitors and local anesthetic is a Ca2+ channel blocker.

Local anesthetics, such as lidocaine, work by blocking voltage-gated sodium channels. This prevents the movement of sodium ions across the neuronal membrane and inhibits the conduction of nerve impulses. By blocking sodium channels, local anesthetics can cause numbness and pain relief.

NSAIDs (nonsteroidal anti-inflammatory drugs), on the other hand, work by inhibiting an enzyme called cyclooxygenase (COX). By blocking COX, NSAIDs reduce the production of inflammatory mediators, helping to alleviate pain, inflammation, and fever.