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Reverse CAC: Requires how many NADH and ATP?

a) 1 NADH, 1 ATP
b) 2 NADH, 0 ATP
c) 0 NADH, 2 ATP
d) 3 NADH, 1 ATP

1 Answer

3 votes

Final answer:

In the normal Citric Acid Cycle, each turn yields 3 NADH and generates 1 GTP (which is equivalent to ATP). The reverse process is not physiologically relevant and does not normally occur.

Step-by-step explanation:

The question pertains to the Citric Acid Cycle (CAC) and how many NADH and ATP are produced in one turn. Each turn of the CAC produces 3 NADH and 1 GTP, which can be converted to ATP. Therefore, the reverse of the Citric Acid Cycle would theoretically consume equivalents in reverse, but this process does not normally occur in the reverse direction and is not energetically favorable. However, based on the provided options and assuming a hypothetical reverse process, the closest answer would be (d) 3 NADH, 1 ATP, considering the normal forward direction of the cycle. Yet, it's important to mention that the physiological relevance of the reverse operation of the CAC is minimal as cells typically do not run this cycle in reverse.

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