Final answer:
Medicare is the primary insurance for the 22-year-old male with ESRD. Blue Cross Blue Shield and Medicaid may provide secondary coverage.
Step-by-step explanation:
The primary insurance for the 22-year-old male with End-Stage Renal Disease (ESRD) would be the Medicare card. Medicare is a federal health insurance program that primarily provides coverage for individuals with ESRD, regardless of age. Blue Cross Blue Shield and Medicaid may provide secondary coverage to fill in the gaps not covered by Medicare.