Final answer:
The nurse should instruct the client to avoid taking Sildenafil within 24 hours of using nitroglycerin.
Step-by-step explanation:
Nitroglycerin is used to relieve chest pain in heart disease. It is believed to work by releasing nitric oxide, which is a vasodilator. In order for nitroglycerin to be effective, it is important to avoid certain medications that may interact with it. The nurse should instruct the client to avoid taking Sildenafil within 24 hours of using nitroglycerin. Sildenafil is a medication used to treat erectile dysfunction and pulmonary arterial hypertension, and it can interact with nitroglycerin to cause a dangerous drop in blood pressure.