Final answer:
A clinical study was conducted to determine the toxicity of niacin in adult males. The study investigated the effects of consuming a diet without niacin for 2 weeks. Niacin is an essential nutrient required to prevent deficiency diseases.
Step-by-step explanation:
A clinical study was conducted to determine the toxicity of niacin in a group of 50 adult male humans. During the first 2 weeks of the study, the group consumed a formula diet that was nutritionally balanced but did not contain niacin. The purpose of this study was to investigate how much niacin can be considered toxic when consumed above the daily requirement.
Niacin is an essential nutrient and is required in the diet to prevent niacin deficiency diseases. The daily requirement for niacin is typically between 15-20 mg/day. However, the actual niacin requirements can vary depending on the protein content in the diet, as niacin can also be synthesized from the amino acid tryptophan.
In this study, the participants were monitored closely to observe any adverse effects or toxicity symptoms that may arise due to the absence of niacin in their diet.