Question

What is an advantage of In-111 labeled leukocyte imaging over Tc-99m HMPAO labeled leukocyte imaging?

A) Longer half-life
B) Higher resolution
C) Lower radiation exposure
D) Faster imaging time

Answer 1

Indium-111 labeled leukocyte imaging offers the advantage of a longer half-life compared to technetium-99m HMPAO labeled leukocyte imaging, allowing for extended observation periods in medical diagnostic procedures.

Step-by-step explanation:

The advantage of using In-111 (indium-111) labeled leukocyte imaging compared to Tc-99m HMPAO (technetium-99m hexamethylpropyleneamine oxime) labeled leukocyte imaging is primarily A) Longer half-life. While Tc-99m is a commonly used isotope in medical diagnostic procedures due to its easy production and the fact that the short 6-hour half-life limits radiation exposure to the patient, In-111 has a longer half-life of about 2 to 3 days, which allows for extended imaging times. This is particularly beneficial for leukocyte imaging, where tracking the activity and location of white blood cells over a longer period can be necessary for identifying infections or inflammation.