Final answer:
A major difference between prokaryotic cells and eukaryotic cells is that eukaryotic cells have more extensive inner membrane systems and a larger number of intracellular organelles than prokaryotic cells. Prokaryotic cells lack membrane-bound organelles and have a simpler internal structure.
Step-by-step explanation:
There are many differences between prokaryotic and eukaryotic cells. One major difference is that eukaryotic cells tend to have much more extensive inner membrane systems and larger numbers of intracellular organelles than do prokaryotes. Eukaryotic cells contain complex organelles, such as the nucleus, mitochondria, and Golgi apparatus, which carry out various functions in the cell. On the other hand, prokaryotic cells lack these membrane-bound organelles and have a simpler internal structure.