Final answer:
Eukaryotic cells are generally larger and have membrane-bound organelles, including a true nucleus, whereas prokaryotic cells are smaller with genetic material in a nucleoid.
Step-by-step explanation:
The difference between prokaryotic and eukaryotic cells can be found in their structure and complexity. Eukaryotic cells are generally larger than prokaryotic cells, have membrane-bound organelles, and possess a true nucleus, meaning their DNA is surrounded by a membrane. In contrast, prokaryotic cells lack these membrane-bound organelles and instead have their genetic material contained in a region called the nucleoid, which is not enclosed by a membrane.
Among the options provided, option B accurately describes a difference between prokaryotic and eukaryotic cells: B. Eukaryotic cells are generally larger than prokaryotic cells.