145k views
3 votes
What percentage of NK cells have the appearance of large granular lymphocytes

1 Answer

5 votes

Final answer:

Natural Killer (NK) cells, a type of lymphocytes, represent a fraction of all leukocytes and have the appearance of large granular lymphocytes, which are 10-14 µm in size. They have more granules and a smaller nucleus-to-cytoplasm ratio, as well as nuclei that absorb Wright, stain well, appearing dark under a microscope.

Step-by-step explanation:

Natural Killer (NK) cells are a type of lymphocytes and have the appearance of large granular lymphocytes. Although the question does not specify an exact percentage regarding how many NK cells have this appearance, it is known that lymphocytes in general, which include NK cells, account for about 20-30 percent of all leukocytes in the blood. Lymphocytes can range in size, but large granular lymphocytes (likely referring to NK cells and large granular T cells) are typically in the range of 10-14 µm and have a smaller nucleus-to-cytoplasm ratio and visibly more granules. NK cells are also characterized by their large nuclei that actively absorb Wright stain and therefore appear dark-colored under a microscope.

User Steve Moser
by
8.1k points